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The predicted Day 5 nirmatrelvir exposure parameters in adult subjects with mild-to-moderate COVID-19 who were treated with PAXLOVID in EPIC-HR are presented in Table 3. Do not use PAXLOVID with avanafil because a safe and effective avanafil dosage regimen has not been established. Co-administration contraindicated due to the potential for opioid withdrawal symptoms [see Contraindications (4)].

Cialis is primarily used as a treatment for erectile dysfunction (ED), but in some cases, it’s also used for treating the signs and symptoms of benign prostatic hyperplasia (BPH). If, after taking Cialis, Tadalafil, or any other ED drug, you find yourself with a painful erection for 4 hours or more, seek urgent medical advice. You may be suffering from Priapism